The STEA2 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to PUMPCn, STEAP2, and STMP. This antibody recognizes Human, and Mouse antigen. The STEA2 Antibody (Center) has been validated for the following applications: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
This gene is a member of the STEAP family and encodes a
multi-pass membrane protein that localizes to the Golgi complex,
the plasma membrane, and the vesicular tubular structures in the
cytosol. A highly similar protein in mouse has both ferrireductase
and cupric reductase activity, and stimulates the cellular uptake
of both iron and copper in vitro. Increased transcriptional
expression of the human gene is associated with prostate cancer
progression. Alternate transcriptional splice variants, encoding
different isoforms, have been characterized